A full list of publications from our lab can be found here.
2021
Saba J, Cao X, Landick R. 2021. Bacterial transcription continues to surprise: activation by alarmone-mediated σ-factor tethering. Mol Cell. 81, 8-9. https://doi.org/10.1016/j.molcel.2020.12.031
2020
Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, DarsProc Natl Acad Sci U S A. 117, 30423-30432. https://doi.org/10.1073/pnas.2013706117
2020. The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.Proc Natl Acad Sci U S A. 117, 29658-29668. https://doi.org/10.1073/pnas.2010087117
, Landick R, Do 2020. A majority of Rhodobacter sphaeroides promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation.Stoneman HR, Wrobel RL, Place M, Graham M, Krause DJ, De Chiara M, Liti G, Schacherer J, Landick R, Gasch AP, Sato TK, Hittinger CT. 2020. CRISpy-Pop: a web tool for designing CRISPR/Cas9-driven genetic modifications in diverse populations. G3 (Bethesda). 10, 4287-4294. https://doi.org/10.1534/g3.120.401498
Kurumbang NP, Vera JM, Hebert AS, Coon JJ, Landick R. 2020. Heterologous expression of a glycosyl hydrolase and cellular reprogramming enable Zymomonas mobilis growth on cellobiose. PLoS One. 15, e0226235. https://doi.org/10.1371/journal.pone.0226235
Vera JM, https://doi.org/10.1128/mSystems.00250-20
Landick R. 2020. Genome-scale transcription-translation mapping reveals features of Zymomonas mobilis transcription units and promoters. mSystems. 5, e00250-20.Liu Y, Ghosh IN, Martien JI, Zhang Y, Amador-Noguez D, Landick R. 2020. Regulated redirection of central carbon flux enhances anaerobic production of bioproducts in Zymomonas mobilis. Metab Eng. 61, 261-274. https://doi.org/10.1016/j.ymben.2020.06.005
Harden TT, Herlambang KS, Chamberlain M, Lalanne JB, Wells CD, Li GW, Landick R, Hochschild A, Kondev J, Gelles J. 2020. Alternative transcription cycle for bacterial RNA polymerase. Nat Commun. 11, 448. https://doi.org/10.1038/s41467-019-14208-9
2019
Zhang Y, Vera JM, Xie D, Serate J, Pohlmann E, Russell JD, Hebert AS, Coon JJ, Sato TK, Landick R. 2019. Multiomic fermentation using chemically defined synthetic hydrolyzates revealed multiple effects of lignocellulose-derived inhibitors on cell physiology and xylose utilization in Zymomonas mobilis. Front Microbiol. 10, 2596. https://doi.org/10.3389/fmicb.2019.02596
Kim J, Tremaine M, Grass JA, Purdy HM, Landick R, Kiley PJ, Reed JL. 2019. Systems metabolic engineering of Escherichia coli improves coconversion of lignocellulose-derived sugars. Biotechnol J. 14, e1800441. https://doi.org/10.1002/biot.201800441
Shen BA, Landick R. 2019. Transcription of bacterial chromatin. J Mol Biol. 431, 4040-4066. https://doi.org/10.1016/j.jmb.2019.05.041
Kang JY, Mishanina TV, Landick R, Darst SA. 2019. Mechanisms of transcriptional pausing in bacteria. J Mol Biol. 431, 4007-4029. https://doi.org/10.1016/j.jmb.2019.07.017
Liu Y, Landick R, Raman S. 2019. A regulatory NADH/NAD+ redox biosensor for bacteria. ACS Synth Biol. 8, 264-273. https://doi.org/10.1021/acssynbio.8b00485
Stumper SK, Ravi H, Friedman LJ, Mooney RA, Corrêa IR, Gershenson A, Landick R, Gelles J. 2019. Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. eLife. 8, e40576. https://doi.org/10.7554/eLife.40576
Bellecourt MJ, Ray-Soni A, Harwig A, Mooney RA, Landick R. 2019. RNA polymerase clamp movement aids dissociation from DNA but is not required for RNA release at intrinsic terminators. J Mol Biol. 431, 696-713. https://doi.org/10.1016/j.jmb.2019.01.003
Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. 2019. The elemental mechanism of transcriptional pausing. eLife. 8, e40981. https://doi.org/10.7554/eLife.40981
Ghosh IN, Martien J, Hebert AS, Zhang Y, Coon JJ, Amador-Noguez D, Landick R. 2019. OptSSeq explores enzyme expression and function landscapes to maximize isobutanol production rate. Metab Eng. 52, 324-340. https://doi.org/10.1016/j.ymben.2018.12.008