Recent Publications

A full list of publications from our lab can be found here.


Saba J, Cao X, Landick R. 2021. Bacterial transcription continues to surprise: activation by alarmone-mediated σ-factor tethering. Mol Cell. 81, 8-9.


Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, Darst SA, Campbell EA. 2020. The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc Natl Acad Sci U S A. 117, 30423-30432.

Henry KK, Ross W, Myers KS, Lemmer KC, Vera JM, Landick R, Donohue TJ, Gourse RL. 2020. A majority of Rhodobacter sphaeroides promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation. Proc Natl Acad Sci U S A. 117, 29658-29668.

Stoneman HR, Wrobel RL, Place M, Graham M, Krause DJ, De Chiara M, Liti G, Schacherer J, Landick R, Gasch AP, Sato TK, Hittinger CT. 2020. CRISpy-Pop: a web tool for designing CRISPR/Cas9-driven genetic modifications in diverse populations. G3 (Bethesda). 10, 4287-4294.

Myers KS, Vera JM, Lemmer KC, Linz AM, Landick R, Noguera DR, Donohue TJ. 2020. Genome-wide identification of transcription start sites in two Alphaproteobacteria, Rhodobacter sphaeroides 2.4.1 and Novosphingobium aromaticivorans DSM 12444. Microbiol Resour Announc. 9, e00880-20.

Kurumbang NP, Vera JM, Hebert AS, Coon JJ, Landick R. 2020. Heterologous expression of a glycosyl hydrolase and cellular reprogramming enable Zymomonas mobilis growth on cellobiose. PLoS One. 15, e0226235.

Vera JM, Ghosh IN, Zhang Y, Hebert AS, Coon JJ, Landick R. 2020. Genome-scale transcription-translation mapping reveals features of Zymomonas mobilis transcription units and promoters. mSystems. 5, e00250-20.

Liu Y, Ghosh IN, Martien JI, Zhang Y, Amador-Noguez D, Landick R. 2020. Regulated redirection of central carbon flux enhances anaerobic production of bioproducts in Zymomonas mobilis. Metab Eng. 61, 261-274.

Harden TT, Herlambang KS, Chamberlain M, Lalanne JB, Wells CD, Li GW, Landick R, Hochschild A, Kondev J, Gelles J. 2020. Alternative transcription cycle for bacterial RNA polymerase. Nat Commun. 11, 448.


Zhang Y, Vera JM, Xie D, Serate J, Pohlmann E, Russell JD, Hebert AS, Coon JJ, Sato TK, Landick R. 2019. Multiomic fermentation using chemically defined synthetic hydrolyzates revealed multiple effects of lignocellulose-derived inhibitors on cell physiology and xylose utilization in Zymomonas mobilis. Front Microbiol. 10, 2596.

Lal PB, Wells FM, Lyu Y, Ghosh IN, Landick R, Kiley PJ. 2019. A markerless method for genome engineering in Zymomonas mobilis ZM4. Front Microbiol. 10, 2216.

Kim J, Tremaine M, Grass JA, Purdy HM, Landick R, Kiley PJ, Reed JL. 2019. Systems metabolic engineering of Escherichia coli improves coconversion of lignocellulose-derived sugars. Biotechnol J. 14, e1800441.

Shen BA, Landick R. 2019. Transcription of bacterial chromatin. J Mol Biol. 431, 4040-4066.

Kang JY, Mishanina TV, Landick R, Darst SA. 2019. Mechanisms of transcriptional pausing in bacteria. J Mol Biol. 431, 4007-4029.

Liu Y, Landick R, Raman S. 2019. A regulatory NADH/NAD+ redox biosensor for bacteria. ACS Synth Biol. 8, 264-273.

Stumper SK, Ravi H, Friedman LJ, Mooney RA, Corrêa IR, Gershenson A, Landick R, Gelles J. 2019. Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. eLife. 8, e40576.

Bellecourt MJ, Ray-Soni A, Harwig A, Mooney RA, Landick R. 2019. RNA polymerase clamp movement aids dissociation from DNA but is not required for RNA release at intrinsic terminators. J Mol Biol. 431, 696-713.

Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. 2019. The elemental mechanism of transcriptional pausing. eLife. 8, e40981.

Ghosh IN, Martien J, Hebert AS, Zhang Y, Coon JJ, Amador-Noguez D, Landick R. 2019. OptSSeq explores enzyme expression and function landscapes to maximize isobutanol production rate. Metab Eng. 52, 324-340.